Hopf bifurcation of a free boundary problem modeling tumor growth with angiogenesis and two time delays

نویسندگان

چکیده

This paper concerns a free boundary problem modeling tumor growth with angiogenesis and two time delays. The delays represent the taken for cells to undergo mitosis modify rate of cell loss because apoptosis, respectively. We study stability stationary solutions find that Hopf bifurcation occurs under some conditions, which extends results Xu. Furthermore, numerical simulations are performed investigate relationship among angiogenesis, bifurcation.

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ژورنال

عنوان ژورنال: Chaos Solitons & Fractals

سال: 2021

ISSN: ['1873-2887', '0960-0779']

DOI: https://doi.org/10.1016/j.chaos.2021.111578